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Tirzepatide Tirzepatide sold as Mounjaro for diabetes and Zepbound for obesity is a dual agonist at both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

These data will also be collected following knee replacement at 3- and 6-month follow-ups.

OT and AVP: The neuropeptide hormones OT and AVP belong to the same superfamily, and genetic variants in OXT , OXTR , arginine vasopressin receptor 1a ( AVPR1a ) and CD38 (lately demonstrated as essentiall for social behaviour because it mediates oxytocin secretion) have been verified to be associated with autism