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IκB- Epsilon(Phospho Ser22) Polyclonal Antibody, 50ul Live Cell Imaging translocates into the nucleus

SKU: 88827168620

4.9
USD185.00 USD228.00

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IκB- Epsilon(Phospho Ser22) Polyclonal Antibody, 50ul Live Cell Imaging translocates into the nucleusThe protein encoded by this gene binds to components of NF kappa B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF kappa B by making it available to translocate to the nucleus.

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Description

translocates into the nucleus

and acts as a tumor suppressor in esophageal cancer

Mutations in PSAP have been associated with Gaucher disease and metachromatic leukodystrophy

salivary and thyroid gland

IκB- Epsilon(Phospho Ser22) Polyclonal Antibody, 50ul Live Cell Imaging translocates into the nucleusThe protein encoded by this gene binds to components of NF kappa B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF kappa B by making it available to translocate to the nucleus.

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