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doi: 10.1016/j.regpep.2004.06.001

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There are various reasons for this, including the high cost and limited access to the drugs, but side effects particularly nausea may cause some people to give up on their medications before they reach their weight loss goals or improve their Type 2 diabetes

GLP-1 receptors are also widely expressed in the central nervous system, including the brainstem, cerebellum, hippocampus, cortex, hypothalamus, and amygdala [7, 10, 11]