Necrostatin-1 faxine Hydrochloride CAS Number: 101831-37-2
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Necrostatin-1 faxine Hydrochloride CAS Number: 101831-37-2Necrostatin 1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin 1 functions as an allosteric inhibitor of the death domain receptor associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin 1 does not present any perturbation of the Fas TNFR triggered canonical apoptosis cascade. Necrostatin 1 inhibits RIP1
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