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For example, eicosatetraenoic acid (EPA), an -3 LCPUFA, can induce adaptive autophagy in BMSCs by binding to GPR120, counteracting apoptosis, and facilitating differentiation into osteoblasts [45,48]

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The double membranes structure of mitochondria provides an ideal location for ferroptosis, and some researchers have observed mitochondrial impairment in patients with ferroptosis (Sha et al., 2021)