This combination treatment alleviated multiple disorders in in vivo experiments, including cardiomyocyte hypertrophy, glucose and insulin tolerance, and Alzheimers disease, and is currently being tested in multiple clinical studies for different age-related diseases

The results were striking: Genes upregulated by GHK-Cu include: Collagen I, III, and VII synthesis genes (structural repair) Decorin and proteoglycan genes (extracellular matrix integrity) Antioxidant defense genes (SOD2, catalase, glutathione peroxidase) BDNF and nerve growth factor genes (neural repair and neuroprotection) Anti-inflammatory cytokine genes (IL-10, TGF-1) Angiogenesis genes (VEGF, angiopoietin new blood vessel formation) Stem cell self-renewal pathways Genes downregulated by GHK-Cu include: Pro-inflammatory cytokines (TNF-, IL-6, IL-1) Matrix metalloproteinases MMP-1, MMP-3 (enzymes that degrade collagen and connective tissue) Oxidative stress genes Pathways associated with cancer progression and metastasis The pro-inflammatory gene suppression is particularly notable
En France, selon la confrence de consensus de 2001 la Socit nationale franaise de gastroentrologie, le taux d'incidence est de 22 pour 100 000 (population ge de plus de 15 ans)
It's a functional marker it tells you the gut lining is not just intact but actually working