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Manic Fringe Polyclonal Antibody, 100ul Shakers this protein should not be

SKU: 67615037154

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Manic Fringe Polyclonal Antibody, 100ul Shakers this protein should not beMFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked

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Description

this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B)

This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response

Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes

The encoded protein is a calcium-independent synaptotagmin

Manic Fringe Polyclonal Antibody, 100ul Shakers this protein should not beMFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked

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