CHST5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Cytochrome c oxidase I (COX1)

Cytochrome c oxidase I (COX1) also known as mitochondrially encoded cytochrome c oxidase I (MT-CO1) is a protein that in humans is encoded by the MT-CO1 gene

Unlike the rat homolog| the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements

This gene is a member of a conserved family of genes that share a common DNA-binding domain

This protein interacts with the transforming growth factor (TGF)-beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators

CHST5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries Cytochrome c oxidase I (COX1)The protein encoded by this gene belongs to the Gal GalNAc GlcNAc 6 O sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N acetylgalactosamine (GalNAc), or N acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O linked sugars of mucin type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in