TYW2 Rabbit Polyclonal Antibody, 20ul Enzymes & Activity Assays Mutations in this gene have

Mutations in this gene have been associated with several diseases

GRIN2C encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor

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Mutations in this gene may play a role in familial idiopathic basal ganglia calcification

TYW2 Rabbit Polyclonal Antibody, 20ul Enzymes & Activity Assays Mutations in this gene haveWybutosine (yW) is a hypermodified guanosine at the 3 prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki 2006).