IL-1Beta Polyclonal Antibody, 100ul[BT-AP04469] Peptide Library The import of proteins with

The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex

Experimental confirmation may be lacking for some isoforms

Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner

A chromosomal translocation (X

IL-1Beta Polyclonal Antibody, 100ul[BT-AP04469] Peptide Library The import of proteins withInterleukin 1 beta encoded by IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1 ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase 2