Orexin R-1 Polyclonal Antibody, 100ul[BT-AP06705] Roller Bottles Orphan receptor with constitutive G(i)

Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP

tissue specificity:Highly expressed in placenta and lung

It is a receptor for hyaluronic acid (HA) and can also interact with other ligands

Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease

Orexin R-1 Polyclonal Antibody, 100ul[BT-AP06705] Roller Bottles Orphan receptor with constitutive G(i)The hypocretin receptor 1 encoded by HCRTR1 is a G protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G protein coupled receptor that binds orexin A and orexin B.