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Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays The gene structure (number and

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Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays The gene structure (number andNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

The gene structure (number and length of exons) is similar among family members

AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium

Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures

This gene is expressed in different carcinomas

Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays The gene structure (number andNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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