PPR1A Polyclonal Antibody, 50ul Supplements Substrates of the encoded protein

Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin

It is the rate-limiting enzyme in the synthesis of catecholamines

The isoform type 3 can inhibit the function of isoforms type

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the Catalytic activity is acquired

PPR1A Polyclonal Antibody, 50ul Supplements Substrates of the encoded proteinInhibitor of protein phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I 1 activity in many tissues. I 1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I 1 is inactivated by calcineurin (or PP2B). Does not inhibit type 2 phosphatases.,PTM: Phosphorylation of Thr 35 is