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Malondialdehyde (MDA) is a biomarker of oxidative stress in diabetic CVD which is produced from lipid peroxidation of the polyunsaturated fatty acids that promoted atherosclerotic plaque buildup in diabetic mice (82)

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mean baseline WOMAC physical function subscale score: 5.8 points) who were randomly assigned 1:1:1 to receive either retatrutide 9 mg, retatrutide 12 mg or placebo by subcutaneous injection