RGRF1 Polyclonal Antibody, 50ul Cell Culture Dishes Mutations in this gene result

Mutations in this gene result in familial dysbetalipoproteinemia

The physiological function has not been determined but it is known that the protein binds heme

TERF2IP encodes a protein that is part of a complex involved in telomere length regulation

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane

RGRF1 Polyclonal Antibody, 50ul Cell Culture Dishes Mutations in this gene resultThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta gamma subunit. Mouse studies