Ku-70(Phospho Ser5) Polyclonal Antibody, 20ul Gel & Buffers MIM 612725) (Stefansson and Brautigan|
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Ku-70(Phospho Ser5) Polyclonal Antibody, 20ul Gel & Buffers MIM 612725) (Stefansson and Brautigan|The p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with
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