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Latrophilin-1 Polyclonal Antibody, 100ul CellSafe™ PTM:Binds keratan sulfate chains

SKU: 16554205355

4.5
USD141.00 USD165.00

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Latrophilin-1 Polyclonal Antibody, 100ul CellSafe™ PTM:Binds keratan sulfate chainsADGRL1 encodes a member of the latrophilin subfamily of G protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non human species, endogenous proteolytic cleavage within a cysteine rich GPS (G protein coupled receptor proteolysis site) domain resulted in two subunits (a large extracellular N terminal cell adhesion subunit and a subunit with substantial similarity to the secretin

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Description

PTM:Binds keratan sulfate chains

The encoded enzyme associates with AppBp1| an amyloid beta precursor protein binding protein| to form a heterodimer| and then the enzyme complex activates NEDD8| a ubiquitin-like protein| which regulates cell division| signaling and embryogenesis

Members of this family are important during development

and is found to be upregulated in multiple cancer cell lines

Latrophilin-1 Polyclonal Antibody, 100ul CellSafe™ PTM:Binds keratan sulfate chainsADGRL1 encodes a member of the latrophilin subfamily of G protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non human species, endogenous proteolytic cleavage within a cysteine rich GPS (G protein coupled receptor proteolysis site) domain resulted in two subunits (a large extracellular N terminal cell adhesion subunit and a subunit with substantial similarity to the secretin

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