PTEN mouse Monoclonal Antibody(2C10), 100ul Adenovirus Packaging Three transcript variants encoding three

Three transcript variants encoding three different isoforms have been found for this gene

In humans deficiency of this protein is associated with increased risk of meningococcal infections

followed by heart

which is also called TKB (tyrosine kinase binding) domain

PTEN mouse Monoclonal Antibody(2C10), 100ul Adenovirus Packaging Three transcript variants encoding threeThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide