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This metabolic mechanism explains why three-month weight loss often exceeds expectations compared to diet alone

Turk J Pharm Sci 18(5):637644 Seo ES, Oh BK, Pak JH, Yim SH, Gurunathan S, Kim YP, Lee KJ (2013) Acteoside improves survival in cecal ligation and puncture-induced septic mice via blocking of high mobility group box 1 release

This means it stays bioactive in your system much longer, provides more sustained anabolic signaling, and requires less frequent administration compared to regular IGF-1