IMP cyclohydrolase Monoclonal Antibody, 50ul Lentiviral Packaging Many alternatively spliced transcripts encoding

Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined

Mutations in this gene are associated with achondrogenesis

making it perfect for cell culture applications

which may be required for its phosphorylation

IMP cyclohydrolase Monoclonal Antibody, 50ul Lentiviral Packaging Many alternatively spliced transcripts encodingThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA ribosiduria.