PKN3 Polyclonal Antibody, 100ul Antibody Humanization Muatations in this gene cause

Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)

Weakly expressed in the kidney

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells

Mutations in this gene are associated with nail-patella syndrome

PKN3 Polyclonal Antibody, 100ul Antibody Humanization Muatations in this gene causeCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation: Two specific sites, Thr 718 (activation loop of the kinase domain) and Thr 860 (turn motif), need to be phosphorylated for its full activation.,Contributes to invasiveness in malignant prostate cancer.,PTM: Autophosphorylated.,Belongs to the protein kinase superfamily. AGC Ser Thr protein kinase family. PKC