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In two groups, acute necrotizing pancreatitis was induced by retrograde intraductal infusion of 3% sodium taurocholate

Interestingly, loss of muscle mass in itself appears not to be associated with functional decline and disability [51] but rather maintenance of muscle strength is key to preventing functional decline [52], with randomised controlled trials (RCTs) demonstrating the benefit of resistance training in older adults [53]

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Important factors for the loading phase include: Severity of initial deficiency Presence of neurological symptoms Patients overall health status Response to initial doses as assessed through follow-up laboratory tests By following this guideline, doctors can quickly restore vitamin B12 levels