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[40] report that oral ALA supplementation (1200 mg/12 weeks) resulted in a significant reduction in the serum leptin concentration and a noticeable elevation in the adiponectin-to-leptin ratio in patients with non-alcoholic fatty liver disease

However, a serious and often irreversible vision condition known as Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) has emerged in medical reporting and research as a potential concern