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L-Arginine is a precursor of nitric oxide, which is necessary for the healthy dilation of blood vessels, circulation, and blood flow

Two reviews on recent clinical trials testing CoQ 10 supplementation reported the lack of improvement in motor functions in patients with neurodegenerative diseases, which led the authors to conclude that the use of CoQ 10 in these patients is unnecessary (Liu and Wang, 2014

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The authors thank Professor Patricia Brubaker, Departments of Physiology and Medicine, Canada Research Chair in Vascular and Metabolic Biology, University of Toronto for critical reading of the manuscript