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Importantly, the transcriptional and metabolic adjustments observed here are best interpreted as secondary adaptive responses enabled by stress alleviation, rather than as direct induction of these pathways by the NP themselves

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Insulin Sensitivity And Decreased Diabetes Risk Many PCOS patients deal with insulin resistance (or impaired insulin sensitivity), which occurs when the bodys cells dont respond properly to the insulin released by the pancreas

A1AT also has an effect on B lymphocytes, reducing their proliferation and function, as demonstrated in murine models of autoimmune diseases mediated by autoantibodies, such as rheumatoid arthritis, indicating a possible exploitation of A1AT as a therapeutic agent in autoimmune diseases ( Figure 2 )