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For example, Wellbutrin is contraindicated for anyone who is: Diagnosed with a seizure disorder Taking other drugs that contain bupropion Diagnosed with bulimia or anorexia nervosa Undergoing an abrupt discontinuation of alcohol or sedatives Taking a monoamine oxidase inhibitor (MAOI) or has taken one within 14 days Allergic to bupropion Phentermine is contraindicated for anyone who has or is: A history of heart disease or heart failure Taken a monoamine oxidase inhibitor (MAOI) in the past 14 days Hyperthyroidism Glaucoma Agitation A history of drug abuse A hypersensitivity to the sympathomimetic amines Pregnant or breastfeeding Other warnings Wellbutrin has a boxed warning, also called a black box warning, because of its potential for suicidal thoughts and behaviorespecially in children, teenagers, and young adults

Currently, clinical trials are underway to evaluate the safety and efficacy of tirzepatide in patients with heart failure

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