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It is directly involved in creating energy for the cell through what is known as the electron transport chain

One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)

suggest that DSIP interacts with components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ)

The prescribing information for isotretinoin states that "blood lipid determinations should be performed before isotretinoin is given and then at intervals until the lipid response to isotretinoin is established" [1]