GPRC6A Polyclonal Antibody, 50ul Culture Tubes 3 and an unprocessed pseudogene

3 and an unprocessed pseudogene has been assigned to 16p12-p11

Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP)

and these opposite actions are thought to be mediated by two classes of receptors

This gene is a member of the protein-tyrosine kinase oncogene family

GPRC6A Polyclonal Antibody, 50ul Culture Tubes 3 and an unprocessed pseudogeneMembers of family C of the G protein coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid sensing motif linked to an intramembranous 7 transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N terminal domain (summary by Pi et al. 2005 [PubMed 16199532]).