LEKTI Polyclonal Antibody, 100ul Gene Editing The orthologous mouse gene is

The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele

The encoded protein occurs in certain cell types as either an intracellular

SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000)

This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans

LEKTI Polyclonal Antibody, 100ul Gene Editing The orthologous mouse gene isSPINK5 encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a