XPA Polyclonal Antibody, 20ul Nucleic Acid Amplification APOL2 is a member of

APOL2 is a member of the apolipoprotein L gene family

SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat

Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD (P)H-dependent oxido-reduction of carbonyl groups)

RNA polymerase II transcription regulatory region sequence-specific binding

XPA Polyclonal Antibody, 20ul Nucleic Acid Amplification APOL2 is a member ofXPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.