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On average, many of our clients start to see a difference after a series of 8-12 injections

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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Wan W, You Z, Xu Y, Zhou L, Guan Z, Peng C, et al

3 Because these medications target different pathways, combining them provides complementary benefits: Metformin addresses insulin resistance at the liver and muscle level Wegovy enhances insulin secretion and provides appetite control Together, they offer more comprehensive blood sugar management than either alone The combination is particularly effective because semaglutides glucose-dependent insulin release means it only works when blood sugar is elevated, reducing the risk of hypoglycaemia