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This study population was then divided into two cohorts: (1) semaglutide cohort 668 patients prescribed semaglutide, and (2) non-GLP1-RA anti-diabetes medication cohort 21,445 patients prescribed non-GLP-1RA anti-diabetes medications

The full berberine dosage range used in research protocols is 900 to 1500mg daily, divided into two or three doses taken with meals